By plane
Guatemala City has one big airport called La Aurora. There are daily arrivals from the US, México, El Salvador, Honduras San Pedro Sula, Tegucigalpa, Costa Rica San José, Nicaragua Managua, Panamá. The number of arrivals is in parentheses.
American Airlines (http://www.americanairlin...): Miami 3, Dallas 1 .
United Airlines (http://www.united.com/): Houston 3, Newark on Saturdays.
Copa (http://www.copaair.com/): Panamá 5, Managua 2, San José 2.
Delta (http://www.delta.com/): Atlanta 1, Los Angeles 1.
Taca (http://www.grupotaca.com/...): Miami, Los Angeles, Chicago, Boston, Washington, México, San José 3, El Salvador 3, San Pedro Sula 2, Tegucigalpa 1, Flores 2, Cancún. most outside Central America and Guatemala via San Salvador
Iberia (http://www.iberia.com/): Madrid direct 3 times a week. Rest of the week via San Salvador, San José, or Panamá
Spirit Airlines (http://www.spiritair.com/): Ft Lauderdale
Interjet (http://www.interjet.com.m...)éxico 1
Aeromexico (http://aeromexico.com/mx/...): México 3
The online newspaper Prensa Libre has live arrival and departure information for the airport. (http://www.prensalibre.co...)
There are always taxis at the airport. They operate with fixed prices around $12US from the airport to Zona 10 that are 2-3 times higher than what you would pay for the same distance with an ordinary taxi. If your hotel is in Zona 10, chances are high that there is a free shuttle service.
There is also a bus route operating the road that passes the airport that will take you to Zona 10 at around La Reforma and 12 Calle. If you are going to the old city center Zona 1, many buses go that way from La Reforma or from 7 Avenida that runs in parallel with La Reforma, one block away.
Regular shuttles run to Antigua each day, several times a day from 6AM to 8 PM prices $8-12US per person.
By car
Central American highways CA-1 and CA-9 run through Guatemala City.
CA-1 is part of the Pan-American Highway and comes from the border with Mexico near Tapachula through the western highlands. Within the city, CA-1 is first Avenida Roosevelt, then Boulevar Liberacion and then Bulevar Los Proceres. It then becomes Carretera a El Salvador outside of the city and it leads to the Chinamas border with El Salvador.